Ires Ghielen

15 General introduction References 1. Tysnes, O.B. and A. Storstein, Epidemiology of Parkinson’s disease. Journal of Neural Transmission, 2017. 124 (8): p. 901-905. 2. Bellou, V., et al., Environmental risk factors and Parkinson’s disease: An umbrella review of meta-analyses. Parkinsonism & Related Disorders, 2016. 23 : p. 1-9. 3. Dorsey, E.R., et al., The Emerging Evidence of the Parkinson Pandemic. Journal of Parkinsons Disease, 2018. 8 : p. S3-S8. 4. Parkinson, J., An essay on the shaking palsy. London: Sherwood, Neely and Jones, 1817. 5. Charcot, J.-M., De la paralysie agitante. , in Oeuvres Comple`tes (t 1) Lec¸ons sur les maladies du syste`me nerveux . 1872, A Delahaye: Paris. p. 155-188. 6. Walusinski, O., Jean-Martin Charcot and Parkinson’s disease: Teaching and teaching materials. Revue Neurologique, 2018. 174 (7-8): p. 491-505. 7. Sauerbier, A., et al., Non motor subtypes and Parkinson’s disease. Parkinsonism & Related Disorders, 2016. 22 : p. S41-S46. 8. Weintraub, D. and E. Mamikonyan, The Neuropsychiatry of Parkinson Disease: A Perfect Storm. American Journal of Geriatric Psychiatry, 2019. 27 (9): p. 998-1018. 9. Braak, H., et al., Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiology of Aging, 2003. 24 (2): p. 197-211. 10. Braak, H., et al., Stages in the development of Parkinson’s disease-related pathology. Cell and Tissue Research, 2004. 318 (1): p. 121-134. 11. Cheng, H.C., C.M. Ulane, and R.E. Burke, Clinical Progression in Parkinson Disease and the Neurobiology of Axons. Annals of Neurology, 2010. 67 (6): p. 715-725. 12. D’Iorio, A., et al., Impact of anxiety, apathy and reduced functional autonomy on perceived quality of life in Parkinson’s disease. Parkinsonism & Related Disorders, 2017. 43 : p. 114-117. 13. Quelhas, R. and M. Costa, Anxiety, Depression, and Quality of Life in Parkinson’s Disease. Journal of Neuropsychiatry and Clinical Neurosciences, 2009. 21 (4): p. 413-419. 14. Rahman, S., et al., Quality of life in Parkinson’s disease: The relative importance of the symptoms. Movement Disorders, 2008. 23 (10): p. 1428-1434. 15. Mosley, P.E., R. Moodie, and N. Dissanayaka, Caregiver Burden in Parkinson Disease: A Critical Review of Recent Literature. Journal of Geriatric Psychiatry and Neurology, 2017. 30 (5): p. 235-252. 16. Pontone, G.M., et al., Prevalence of Anxiety Disorders and Anxiety Subtypes in Patients with Parkinson’s Disease. Movement Disorders, 2009. 24 (9): p. 1333- 1338. 1