Ires Ghielen

59 Replication factor analysis in neuropsychiatric PD patients Table S3. Independent samples t-tests results of the comparison of the sample characteristics between the current and the previous [18] patient sample. Outcome measure Mean (sd) Rutten et al. [18] Mean (sd) current sample Difference in mean (CI) t-value (df=415) Significance BAI 14.2 (9.8) 20.3 (11.4) 6.1 (3.94 – 8.26) 5.58 P<0.001 BDI 11.4 (8.0) 18.2 (9.3) 6.8 (5.03 – 8.57) 7.63 P<0.001 Age 64.5 (10.3) 66.1 (9.8) 1.6 (-.53 – 3.73) 1.48 ns UPDRS-III (n=109) 25.8 (12.3) 27.3 (14.8) 1.5 (-1.31 – 4.31) 1.06 ns Disease duration (n=85) 5.1 (5.6) 8.4 (6.9) 3.3 (1.94 – 4.66) 4.81 P<0.001 Abbreviations: BAI = Beck Anxiety Inventory; BDI = Beck Depression Inventory; UPDRS-III = Unified Parkinson’s Disease Rating Sccale – part three (motor examination); MoCA = Montreal Cognitive Assessment, n = amount of patients; sd = standard deviation; CI = Confidence Interval; df = degrees of freedom; ns = nonsignificant. 3