Caroliene Meijndert

127 The effect of implant-abutment connections on peri-implant bone level change Study Random effects model Canullo et al., 2013 Canullo et al., 2017 Canullo et al., 2018 Cooper et al., 2019 (b) Lowy et al., 2019 (a) Mean −0.14 −0.17 −0.09 −0.06 −0.35 −0.05 SD 0.20 0.07 0.06 0.17 0.21 N 20 30 22 32 20 95%−CI [−0.23; −0.06] [−0.26; −0.08] [−0.11; −0.06] [−0.09; −0.04] [−0.41; −0.29] [−0.14; 0.04] −1 −0.5 0 0.5 1 Mean and 95% CI Figure 3. Forest plots for random effects meta-analysis of studies evaluating of bone level change in the PS-parallel group Study Random effects model Cooper et al., 2019 (b) Den Hartog et al., 2016 Den Hartog et al., 2017 Felice et al., 2015 Fu et al., 2014 Gjelvold et al., 2017 Gjelvold et al., 2020 Guarnieri et al., 2016 Hsu et al., 2016 (b) Lowy et al., 2019 (b) Meloni et al., 2015 Raghoebar et al., 2009 Mean −0.47 −0.34 −0.03 −0.25 −0.19 −1.27 −0.63 −0.40 −0.14 −0.74 −0.65 −0.87 −0.54 SD 0.17 0.10 0.20 0.10 0.91 0.54 0.41 0.07 0.47 0.59 0.19 0.13 N 34 27 54 23 26 50 21 13 13 20 30 45 95%−CI [−0.62; −0.33] [−0.40; −0.28] [−0.07; 0.00] [−0.30; −0.19] [−0.23; −0.15] [−1.62; −0.93] [−0.78; −0.48] [−0.58; −0.22] [−0.18; −0.10] [−1.00; −0.48] [−0.91; −0.39] [−0.94; −0.80] [−0.58; −0.50] −1 −0.5 0 0.5 1 Mean and 95% CI Figure 4. Forest plots for random effects meta-analysis of studies evaluating of bone level change in the PM-parallel group iii. Mid-buccal mucosa level changes Twenty study groups reported changes in mid-buccal mucosa level, viz., 12 in the PS- conical group, 3 in the PS-parallel group, and 5 in the PM-parallel connection group. The groups’ pooled mid-buccal mucosa level change per year was 0.05 mm (95%CI: 0.01 to 0.08), composed of 0.04 mm (95%CI: -0.02 to 0.09) in the PS-conical group, 0.08 mm (95%CI: 0.05 to 0.12) in the PS-parallel group, and 0.04 mm (95%CI: -0.08 to 0.16) in the PM-parallel group. A meta-regression analysis revealed no statistically significant difference between the three groups. Forest plots of the random effects meta-analysis are depicted in supplementary figure 5 . 7