Franny Jongbloed

165 6 MORBID OBESITY, BARIATRIC SURGERY AND T-CELL AGING Table S1. Multivariate analysis of the factors MetS, age, CMV-status and gender on relative telomere length and T-cell differentiation status prior to bariatric surgery Model Factors MetS Age CMV-status Gender Model 1: RTL: CD4 + & CD8 + 0.13 0.64 0.47 0.98 Model 2 T-cell phenotype: CD4 + 0.36 0.57 <0.001 0.29 Model 3 T-cell phenotype: CD8 + 0.77 0.03 0.005 0.01 Significant P- values (P<0.05) are depicted in bold. Model = the generalized linear model based on mentioned variables. MetS: MetS vs. no MetS; Age: >50 vs. ≤50 years; CMV-status: CMV+ vs. CMV-; Gender: female vs. male. T-cell phenotype included the following T-cell subsets: naive, CD31 naive, central memory, effector memory, effector memory RA, memory, CD28null and absolute T-cell numbers. MetS = metabolic syndrome; CMV = cytomegalovirus; RTL = relative telomere length.