Franny Jongbloed

202 CHAPTER 8 lower serum creatinine concentration at the outpatient clinic visit ( P= 0.018). Baseline characteristics of all transplant recipients (Table 1B) and the donors of whom biopsies were used for transcriptomic profiling (Table S1) showed no differences between the two groups. Table 1A. Baseline characteristics of living kidney donors Parameter CCPR (n=15) Control (n=20) P- value Age (years) 55 (51-55) 54 (46-59) 0.395 Gender (Male/Female) 4/11 13/7 0.028 BMI (kg/m 2 ) 23.7 (22.4-27.6) 26.0 (26.6-29.1) 0.157 Systolic blood pressure (mm/Hg) 128 (123-137) 128 (122-137) 1.000 Creatinine (mmol/L) 71 (66-78) 80 (71-91) 0.021 CKD-EPI eGFR (mL/min) 86 (72-90) 80 (73-89) 0.672 Urea (mmol/L) 5.3 (4.4-5.8) 5.3 (4.2-6.1) 0.986 Glucose (mmol/L) 5.3 (5.0-5.7) 5.0 (4.8-5.9) 0.217 Albumin (g/L) 47 (44-48) 46 (45-47) 0.398 Triglycerides (mmol/L) 1.22 (0.85-1.50) 1.31 (1.00-1.68) 0.488 Hemoglobin (mmol/L) 8.8 (8.4-9.0) 9.2 (8.7-9.6) 0.031 Trombocytes (10 9 /L) 234 (213-294) 253 (206-289) 0.972 CRP (mg/L) 1.1 (0.7-1.9) 1.5 (0.6-2.4) 0.259 Leukocytes (10 9 /L) 6.6 (5.5-7.4) 6.6 (5.5-7.8) 0.652 Bilirubin (µmol/L) 6 (5-10) 7 (5-12) 0.467 Potassium (mmol/L) 4.4 (4.2-4.6) 4.3 (4.1-4.7) 0.444 Type of donation (R/U/A) 3/3/9 4/12/4 0.083 Side of nephrectomy (Left/Right) 8/7 12/8 0.712 Method used (Laparoscopic/HARP) 12/3 14/6 0.523 Table 1B. Baseline characteristics of kidney transplant recipients Parameter CCPR (n=15) Control (n=20) P- value Age (years) 56 (44-67) 54 (45-58) 0.250 Gender (Male/Female) 8/7 10/10 0.863 Kreatinine (mmol/L) 495 (442-637) 449 (321-902) 0.351 CKD-EPI eGFR (mL/min) 9 (7-11) 11 (5-14) 0.471 Urea (mmol/L) 19.9 (16.2-31.4) 22.6 (15.0-27.1) 0.881 Potassium (mmol/L) 5.4 (4.7-5.8) 4.7 (4.4-5.3) 0.092 Hemoglobin (mmol/L) 6.6 (6.2-7.5) 7.3 (6.6-8.3) 0.166