Franny Jongbloed

230 CHAPTER 8 Table S1. Baseline characteristics of living kidney donors included in the transciptome analysis Parameter CCPR (n=10) Control (n=10) P- value Donors Age (years) 59 (53-61) 51 (44-64) 0.19 Gender (Male/Female) 3/7 5/5 0.39 BMI (kg/m 2 ) 25.6 (23.3-28.0) 25.4 (23.4-26.0) 0.59 Systolic blood pressure (mm/Hg) 130 (124-136) 128 (124-136) 0.89 Creatinine (mmol/L) 74 (68-82) 78 (71-90) 0.15 eGFR (mL/min) 83 (66-90) 75 (72-83) 0.68 Urea (mmol/L) 5.2 (4.8-5.6) 5.2 (4.0-5.4) 0.46 Glucose (mmol/L) 5.3 (5.1-5.7) 5.1 (4.8-5.8) 0.56 Albumin (g/L) 47 (45-48) 45 (45-47) 0.85 Triglycerides (mmol/L) 1.2 (0.9-1.8) 1.3 (1.2-1.5) 0.62 Hemoglobin (mmol/L) 8.7 (8.4-9.1) 8.9 (8.6-9.2) 0.63 Trombocytes (10 9 /L) 241 (222-302) 223 (206-289) 0.48 CRP (mg/L) 1.4 (1.0-2.0) 1.3 (0.8-2.4) 0.30 Leukocytes (10 9 /L) 6.5 (5.6-7.6) 5.9 (5.5-6.9) 1.00 Bilirubin (µmol/L) 8.0 (5.3-10.0) 6.0 (5.0-7.3) 0.31 Potassium (mmol/L) 4.5 (4.3-4.6)1 4.4 (4.1-4.8) 0.86 Type of donation (R/U/A) 3/1/6 1/6/3 0.79 Side of nephrectomy (Left/Right) 6/4 6.4 1.00 Method used (Laparoscopic/HARP) 7/3 7/3 1.00 No significant differences (P<0.05) were seen in the baseline characteristics of both groups. BMI = body mass index; eGFR = estimated glomerular filtration rate using the CKD-EPI formula; CRP = C-reactive protein. Type of donation: R = related; U = unrelated; A = anonymous. HARP = hand-assisted retroperitoneal nephrectomy.

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