Franny Jongbloed

44 CHAPTER 2 Table S2. Top genes downregulated in aged mice fasted for three days Genes AGED downregulated Symbol Log FR P- value Solute carrier family 22, member 7 SLC22A7 -2.670 7.74 E- 05 Major facilitator superfamily domain containing 2A MFSD2A -2.357 2.03 E- 04 Solute carrier family 8, member 1 SLC8A1 -2.302 1.76 E- 04 Antisense Igf2r RNA Airn -2.097 1.17 E- 05 Midkine MDK -1.850 2.84 E- 04 Branched chain amino-acid transaminase 1 BCAT1 -1.686 1.64 E- 03 Carbonix anhydrase IV CA4 -1.680 2.62 E- 06 Isopentenyl-disphosphate delta isomerase 1 IDI1 -1.674 2.25 E- 05 Solute carrier family 9, subfamily A, member 8 SLC9A8 -1.647 1.29 E- 06 Ring finger protein 183 RNF183 -1.606 6.58 E- 05 Top gene lists of downregulated genes in aged-overweight mice fasted for three days, with corresponding symbols, log fold ratios and P- values. All genes with a fold change >5 (log fold ratio (-)1.609) are listed.