Marilen Benner

SUMMARY AND DISCUSSION 233 8 REFERENCES 1. Gellersen B, Brosens JJ. Cyclic Decidualization of the Human Endometrium in Reproductive Health and Failure. Endocr Rev. 2014;35(6):851-905. 2. Critchley HOD, Maybin JA, Armstrong GM, Williams ARW. Physiology of the Endometrium and Regulation of Menstruation. Physiological reviews. 2020;100(3):1149-79. 3. van der Molen RG, Schutten JH, van Cranenbroek B, ter Meer M, Donckers J, Scholten RR, et al. Menstrual blood closely resembles the uterine immune micro-environment and is clearly distinct from peripheral blood. Human reproduction (Oxford, England). 2014;29(2):303-14. 4. Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, et al. Endometrial NK Cells Are Special Immature Cells That Await Pregnancy. Journal of immunology (Baltimore, Md : 1950). 2008;181(3):1869-76. 5. Croy BA, van den Heuvel MJ, Borzychowski AM, Tayade C. Uterine natural killer cells: a specialized differentiation regulated by ovarian hormones. Immunological reviews. 2006;214:161-85. 6. Manaster I, Mandelboim O. The Unique Properties of Uterine NK Cells. Am J Reprod Immunol. 2010;63(6):434-44. 7. Moffett-King A. Natural killer cells and pregnancy. Nature reviews Immunology. 2002;2(9):656-63. 8. Tilburgs T, Roelen DL, van der Mast BJ, van Schip JJ, Kleijburg C, de Groot-Swings GM, et al. Differential distribution of CD4(+)CD25(bright) and CD8(+)CD28(-) T-cells in decidua and maternal blood during human pregnancy. Placenta. 2006;27 Suppl A:S47-53. 9. Kwan M, Hazan A, Zhang J, Jones RL, Harris LK, Whittle W, et al. Dynamic changes in maternal decidual leukocyte populations from first to second trimester gestation. Placenta. 2014;35(12):1027-34. 10. Haller H, Radillo O, Rukavina D, Tedesco F, Candussi G, Petrovic O, et al. An immunohistochemical study of leucocytes in human endometrium, first and third trimester basal decidua. Journal of reproductive immunology. 1993;23(1):41-9. 11. Tilburgs T, Schonkeren D, Eikmans M, Nagtzaam NM, Datema G, Swings GM, et al. Human Decidual Tissue Contains Differentiated CD8⁺ Effector-Memory T Cells with Unique Properties. The Journal of Immunology. 2010;185(7):4470. 12. Powell RM, Lissauer D, Tamblyn J, Beggs A, Cox P, Moss P, et al. Decidual T Cells Exhibit a Highly Differentiated Phenotype and Demonstrate Potential Fetal Specificity and a Strong Transcriptional Response to IFN. Journal of immunology (Baltimore, Md : 1950). 2017;199(10):3406-17. 13. Saito S, Nakashima A, Shima T, Ito M. Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancy. Am J Reprod Immunol. 2010;63(6):601-10. 14. Chaouat G, Ledee-Bataille N, Zourbas S, Ostojic S, Dubanchet S, Martal J, et al. Cytokines, implantation and early abortion: re-examining the Th1/Th2 paradigm leads to question the single pathway, single therapy concept. Am J Reprod Immunol. 2003;50(3):177-86. 15. Acosta-Rodriguez EV, Rivino L, Geginat J, Jarrossay D, Gattorno M, Lanzavecchia A, et al. Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells. Nature Immunology. 2007;8:639.