Marilen Benner

GRAPHICAL SUMMARY 249 9 CHAPTER 4| CLUSTERS OF TOLEROGENIC B CELLS FEATURE IN THE DYNAMIC IMMUNOLOGICAL LANDSCAPE OF THE PREGNANT UTERUS IL-10? Abundance M e m o r y NK T B Reg T B IL-10 • B cells obtained from the fetal-maternal interface gain memory during gestation. • Unsupervised analysis shows B cell subsets with marker expression unique to the uterus. • Decidual B cells are able to secrete IL-10. • Clusters of decidual B cells also contain T cells, including Foxp3 + T cells.