Marilen Benner

283 13 FAIR PRINCIPLES FAIR PRINCIPLES This thesis is based on the results of human studies which were performed in accordance with the principles of the Declaration of Helsinki. All samples were acquired with the approval of the local medical and ethical review board. Study codes, as registered with the Committee on Research Involving Human Subjects Region Arnhem Nijmegen, Nijmegen, the Netherlands, are stated in the Materials and Methods section of the respective chapter. The murine data described in Chapter 7 were acquired in collaboration with the University of Utrecht. Animal procedures were approved by the Ethical Committee for Animal Research of the Utrecht University and conducted according to the European Directive 2010/63/EU on the protection of animals used for scientific purposes (AVD108002016597). Experimental notes are stored on Labguru, a digital lab book platform, and accessible by the associated staff members. Raw data and analyses are stored on the Radboudumc department server (labgk_lmi-research, umcsanfsclp01) in separate folders assigned to each project (Z:\ Sectie HCI_kweek\z049173_Marilen Benner\Projects). These data are backed-up on local servers of the department on a weekly basis. Samples were labeled with an ID to ensure anonymity. All databases which contain or link patient details to sample IDs are password protected. Published data associated with this thesis are accessible on the respective journal website or can be provided by the corresponding author upon request.