Marilen Benner

THREE TYPES OF TREG CONTROL PLACENTAL INFLAMMATION 55 3 Figure 1. Three distinct CD4+ T cell populations express Treg-associated markers. (A and B) Representative FACS plots (A) and percentages (B) of CD25 HI , PD1 HI , and TIGIT+ cells within CD4+ T cells in blood, decidua 6–12 weeks, d.basalis >37 weeks, and d.parietalis >37 weeks. ( C and D) Representative FACS plots (C) and percentages (D) of FOXP3+ and HELIOS+ cells within the four CD4+ T cell types and HELIOS+ cells within CD25 HI FOXP3+ cells in blood, decidua 6–12 weeks, d.basalis >37 weeks, and d.parietalis >37 weeks (n = 8–10). Bars represent median and interquartile range; *p < 0.05, **p < 0.01 and ***p < 0.001. See also Figures S1-S3.

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