Desley van Zoggel

Chapter 3 40 Table 1. Baseline and primary tumour characteristics Total N = 132 Gender Female 37 (28) Male 95 (72) Age(yr)a Median [IQR] 65 [58–71] ASAa I 3 (2) II 107 (81) III 22 (17) Tumour stageb T2 11 (8) T3 92 (70) T4 27 (21) Nodal stagec N0 41 (31) N1 46 (35) N2 41 (31) Neoadjuvant radiotherapy None 36 (27) Radiotherapy 34 (26) Chemoradiotherapy 62 (47) Surgical procedure Sigmoid resection 18 (14) Low anterior resection 67 (51) Abdominoperineal resection 47 (36) Adjuvant therapyd None 113 (86) Chemotherapy 17 (13) Radiotherapy 3 (2) Values in parentheses are percentages unless indicated otherwise. a At time of surgery for recurrent tumour b Missing value in N = 2 c Missing value in N = 4 d One patient received both adjuvant chemotherapy and radiotherapy IQR interquartile range Univariable analyses are shown in Table 3. For overall survival, only resection margin remained significant aftermultivariable analysis (P = 0.034, 95 percent CI 1.059–4.272), with a hazard ratio (HR) of 2.1 for death after an irradical resection. Median survival for patients with an R0 resection was 54 months versus 29 months otherwise.

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