Lateral lymph node recurrence and induction chemotherapy 61 CHAPTER 4 Table 1. Patient and treatment characteristics Total N = 51 Median age, years (range) 63 (39-83) Sex Male 33 (65) Female 18 (35) Stage of primary tumor I 1 (6) II 9 (18) III 39 (76) Type of primary surgery Rectosigmoid resection 8 (18) Low anterior resection 15 (30) Abdominoperineal resection 27 (52) (Neo)adjuvant treatment for primary tumour None 9 (17) Preoperative 5x5 radiotherapy 28 (55) Preoperative long-course radiotherapy 1 (2) Preoperative chemoradiotherapy 8 (16) Postoperative long-course radiotherapy 3 (6) Postoperative chemoradiotherapy 2 (4) Adjuvant chemotherapy for primary tumour No 38 (75) Yes 13 (25) Median interval primary-LRRC surgery, months (range) 44 (10-191) Resectable metastasis prior to or at time of LRRC diagnosis M0 42 (82) M1 9 (18) Neoadjuvant treatment for LRRC None 1 (2) Re-irradiation with chemo 29 (57) Induction chemo, reirradiation with chemo 12 (23) Full course CRT 8 (16) Induction chemo, full-course CRT 1 (2) Median interval between end of CRT and LRRC surgery, weeks (range) Dose of IORT (Gy) 10 (5-40) 0 1 (2) 10 36 (72) 12.5 14 (27) Values in parentheses are percentages unless otherwise specified. LRRC locally recurrent rectal cancer, CRT chemoradiotherapy, IORT intraoperative radiotherapy.
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