Impact of metastases on survival 89 CHAPTER 5 Metastasis-free survival HR CI P-value HR CI P-value 1.00 - 0.84 0.62-1.14 0.260 1.00 - 1.07 0.78-1.46 0.684 1.00 - 1.12 0.72-1.74 0.615 1.00 - 1.32 0.90-1.94 0.150 1.00 - 1.00 - 1.75 1.28-2.40 0.001 1.76 1.27-2.45 0.001 1.00 - 1.04 0.72-1.49 0.838 1.15 0.80-1.66 0.443 1.00 - 2.11 0.78-5.73 0.142 2.34 0.85-6.47 0.102 1.00 - 1.31 0.90-1.90 0.153 1.00 - 1.14 0.76-1.73 0.524 1.00 - 1.00 - 1.43 1.04-1.95 0.026 1.20 0.85-1.69 0.301 1.00 - 1.00 - 0.35 0.05-2.61 0.304 0.29 0.04-2.21 0.231 0.50 0.29-0.86 0.012 0.64 0.35-1.19 0.157 0.48 0.29-0.81 0.006 0.50 0.29-0.86 0.013 1.00 - 1.17 0.60-2.29 0.645 1.07 0.69-1.65 0.767 1.17 0.64-2.15 0.603 1.00 - 1.11 0.74-1.68 0.609 1.00 - 1.00 - 1.47 0.94-2.30 0.092 1.36 0.85-2.17 0.205 3.28 2.19-4.91 <0.001 3.25 2.11-5.02 <0.001 1.00 - 1.32 0.77-2.26 0.315 1.00 - 1.00 - 2.13 1.57-2.89 <0.001 2.25 1.64-3.09 <0.001 ASA, American Society of Anesthesiologists Physical Status; HR, hazard ratio; LAR low anterior resection; LRRC, locally recurrent rectal cancer; TEM, transanal endoscopic microsurgery
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