Desley van Zoggel

Chapter 1 General introduction and outline of the thesis	9
Chapter 2 Preliminary results of a cohort study of induction chemotherapybased treatment for locally recurrent rectal cancer	19
Chapter 3 Improved outcomes for responders after treatment with induction chemotherapy and chemo(re)irradiation for locally recurrent rectal cancer	33
Chapter 4 Local recurrence in the lateral lymph node compartment: improved outcomes with induction chemotherapy combined with multimodality treatment	55
Chapter 5 Impact of a history of metastases or synchronous metastases on survival in patients with locally recurrent rectal cancer	71
Chapter 6 MRI tumour regression grade in locally recurrent rectal cancer	99
Chapter 7 Metabolic positron emission tomography/CT response after induction chemotherapy and chemo(re)irradiation is associated with higher negative resection margin rate in patients with locally recurrent rectal cancer	119
Chapter 8 Summary, discussion and future perspectives	139
Chapter 9 Scientific and societal impact	153
Curriculum vitae	161
Dankwoord	165

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