Femke Mathot
7 Motor results of MSC-seeded nerve allografts 123 CONCLUSION Undifferentiated and differentiated MSCs significantly improved functional outcomes of decellularized allografts at 12 weeks in motor nerves and equaled the autograft results in the majority of outcome measurements. At 16 weeks, outcome measures normalized as expected. Considering clinical applicability, undifferentiated MSCs are more attractive as outcomes did not significantly differ between both cell-types, and differentiation requires increased time and cost. Acknowledgements We thank Roman Thaler, PhD, for assisting with cell culture and differentiation of the Mesenchymal Stem Cells. We thank Patricia F. Friedrich for assistance with the preparations of the experiments.
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