Femke Mathot

3 MSC-seeding on processed nerve allografts 55 CONCLUSION We successfully differentiated MSCs into Schwann-like cells and dynamically seeded them onto a processed nerve allograft. The viability of undifferentiated MSCs and differentiated MSCs was not influenced by the processed nerve allograft. Both cell types distributed equally among the nerve allograft, remained on the surface of the allograft and did not migrate into the graft. Thus, seeding of nerve allografts with Schwann-like MSCs can be further considered for in vivo studies for nerve repair. Conflict of interest statement None of the authors has a conflict of interest. This study was funded by the NIH R01, ‘Bridging the gap: angiogenesis and stem cell seeding of processed nerve allograft’. 1 RO1 NS102360-01A1 Acknowledgements We thank Patricia F. Friedrich for assistance with the preparations of the experiments.

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