Tiam Mana Saffari

222 CHAPTER 10 Table 2. Outcomes of vascular volume. Results were expressed as mean% vessel ± SEM, SEM: Standard error of the mean. dMSC: differentiated mesenchymal stem cells, SIEF: superficial inferior epigastric artery fascial (SIEF) flap, uMSC: undifferentiated mesenchymal stem cells. Groups Vascular volume Control 4.52 ± 0.33 Autograft 2.51 ± 0.26 Allograft 1.35 ± 0.41 SIEF 3.38 ± 0.56 uMSCs + SIEF 5.57 ± 0.72 dMSCs + SIEF 3.16 ± 0.18 Figure 3. Vascular volume of nerve groups at 2 weeks using micro computed tomography (micro CT) . Results of control nerve, autograft, allograft, and allograft wrapped in a pedicled superficial inferior epigastric artery fascial (SIEF) flap, combined with undifferentiated mesenchymal stem cells (uMSC+SIEF) or mesenchymal stem cells differentiated into Schwann cell-like cells (dMSC+SIEF). Results were expressed as a percentage (vessel%) of the total nerve area and given as the mean ± SEM. *Indicates significance at P < 0.05, **P < 0.01, ***P < 0.0001. SEM: Standard error of the mean. Blood vessel morphology Evaluation of the nerve angioarchitecture allowed for determination of the distribution of blood vessels in nerve sample groups. Diameters of blood vessels found in autograft nerves ranged from 0-220 µm, 0-200 µm in allografts and 0-200 µm in control nerves