Tiam Mana Saffari

268 APPENDICES RESEARCH DATA MANAGEMENT The FAIR data principles are guiding principles on how to make data Findable , Accessible , Interoperable and Reusable . All animal experiments were conducted in accordance with institutional, national and international guidelines for animal care and the federal law concerning animal welfare. The studies were reviewed and approved by the Institutional Animal Care and Use Committee (IACUC). Data of the experiments is collected using Labview, Analyze Pro and NIS-Elements software (NIS-Elements BR 4.51.01). Data has been transferred and handled using Excel to calculate the operated/nonoperated ratios in %. These numbers could be used to perform statistical analysis. Data is stored and archived as described with the FAIR principles, see below. Findable Since this is a collaborative research, with an international and interdisciplinary approach to research, the data is stored at the Mayo Clinic. Regular backups are done to protect against accidental or malicious data loss. Encryption is used for safely storing and sending files. Accessible Authentication and authorization is provided once a research fellow is part of the research line and access is granted to the secured folder. Research fellows are in close communication and their fellowships often overlap to provide exchange of knowledge and help to understand and access the data. A group Dropbox is available with progress papers to provide understanding to all research students that are involved in these projects. Each research fellow provides a Dropbox folder with the most recent research knowledge and latest updates that are necessary to conduct and understand the data and projects.