Marieke van Son

152 CHAPTER 8 CONCLUSION This study provides two models for BF prediction in patients with radiorecurrent PCa treated with FS-HDR-BT. Our findings support that both pre- and post-salvage PSA characteristics (PSA level, PSADT, time to PSA nadir, and PSA reduction) are important predictors of BF, in addition to age, tumor volume, and seminal vesicle involvement. These models could aid patient selection, counselling, and guidance at baseline and during follow-up. Potentially, these models can also be used for other salvage tech- niques, for which external validation remains necessary.