Marieke van Son

154 CHAPTER 8 SUPPLEMENTARY FILE B Figure S1 – Kaplan-Meier curve depicting biochemical disease-free survival for the entire FS- HDR-BT group. SUPPLEMENTARY FILE C Predictor Range in dataset used for model building Pre-salvage PSADT (months) 3 – 73 months Age at FS-HDR-BT (years) 59 – 85 years Pre-salvage PSA (ng/ml) 0.4 – 39.0 ng/ml GTV (cm 3 ) 0.5 – 22 cm 3 Time to PSA nadir post-salvage (months) 1 – 25 months PSA reduction post-salvage (%) 0 – 100 % Abbreviations: PSADT=prostate specific antigen doubling time. FS-HDR-BT=focal salvage high- dose-rate-brachytherapy. PSA=prostate specific antigen. GTV=gross tumor volume.