Marieke van Son

155 PREDICTION MODELS FOR BF AFTER FOCAL SALVAGE HDR-BT SUPPLEMENTARY FILE D Model 1 The full regression equation for model 1 is as follows: Or for calculating the predicted survival probability: Where: h(t) = the expected hazard at time t h 0 (t) = the baseline hazard at time t s(t) = the expected survival probability at time t s 0 (t) = the baseline survival at time t (see Table 2 for baseline survival at 12, 24, and 36 months) Age = age in years at time of FS-HDR-BT ln = natural logarithm PSA = pre-salvage PSA level in ng/ml GTV = gross tumor volume in cm 3 PSADT = PSA doubling time in months PSADT’ can be calculated as follows: 8

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