Marieke van Son

CONTENT Chapter 1 General introduction and thesis outline 8 PRIMARY TREATMENT SETTING Chapter 2 Conventional radical versus focal treatment for localized prostate cancer: a propensity score weighted comparison of 6-year tumour control Prostate Cancer and Prostatic Diseases 2021 26 Chapter 3 MRI-guided ultrafocal HDR brachytherapy for localized prostate cancer: median 4-year results of a feasibility study International Journal of Radiation Oncology, Biology, Physics 2019 44 SALVAGE TREATMENT SETTTING Chapter 4 Focal salvage treatment of radiorecurrent prostate cancer: a review of current strategies and future perspectives Cancers 2018 62 Chapter 5 MRI-guided ultrafocal salvage high-dose-rate brachytherapy for localized radiorecurrent prostate cancer: updated results of 50 patients International Journal of Radiation Oncology, Biology, Physics 2020 86 Chapter 6 Health-related quality of life after ultrafocal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer: reporting the patient’s perspective Clinical and Translational Radiation Oncology 2020 106 Chapter 7 Determining the safety of ultrafocal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer: a toxicity assessment of 150 patients Clinical and Translational Radiation Oncology 2020 122 Chapter 8 Development and internal validation of multivariable prediction models for biochemical failure after MRI-guided focal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer Submitted 140 Chapter 9 Re-salvage MRI-guided focal high-dose-rate brachytherapy for locally recurrent prostate cancer Cureus 2018 162 Chapter 10 General discussion and future perspectives 176 Appendices Dutch summary (Nederlandstalige samenvatting) 194 Review committee 199 List of publications 200 Acknowledgements (Dankwoord) 203 Curriculum Vitae 206