Marieke van Son

52 CHAPTER 3 The 4-year BDFS rate was 70% (95% CI 52-93%). MFS was 93% (85-100%) and OS was 100% at 4 years (Figure 3). An explorative Cox-regression analysis only showed a significant hazard ratio (HR) for age: 1.27 (95% CI 1.01-1.59; p=0.04), meaning higher age conveyed higher risk of BF in these patients. Figure 3 – Kaplan-Meier analysis for biochemical disease-free survival (A) and metastases-free survival (B).