Marieke van Son

Chapter 1 General introduction and thesis outline 8
Chapter 2 Conventional radical versus focal treatment for localized prostate cancer: a propensity score weighted comparison of 6-year tumour control 26
Chapter 3 MRI-guided ultrafocal HDR brachytherapy for localized prostate cancer: median 4-year results of a feasibility study 44
Chapter 4 Focal salvage treatment of radiorecurrent prostate cancer: a review of current strategies and future perspectives 62
Chapter 5 MRI-guided ultrafocal salvage high-dose-rate brachytherapy for localized radiorecurrent prostate cancer: updated results of 50 patients 86
Chapter 6 Health-related quality of life after ultrafocal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer: reporting the patient’s perspective 106
Chapter 7 Determining the safety of ultrafocal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer: a toxicity assessment of 150 patients 122
Chapter 8 Development and internal validation of multivariable prediction models for biochemical failure after MRI-guided focal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer 140
Chapter 9 Re-salvage MRI-guided focal high-dose-rate brachytherapy for locally recurrent prostate cancer 162
Chapter 10 General discussion and future perspectives 176
Dutch summary (Nederlandstalige samenvatting) 194
Review committee 199
List of publications 200
Acknowledgements (Dankwoord) 203
Curriculum Vitae 206

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