Dolph Houben

64 CHAPTER 3 Figure 2: Complication rates by study. The calculated means are represented by the blue squares; each square differs in size because the size of the square represents the number of patients included in the study. The blue error bars represent the 95% CI. Re-intervention Re-interventions occurred because of fracture, non-union, infection, recurrence of the tumor, flap failure, deformity, and hardware removal. In 16 studies, re-intervention rates were known. Re- intervention rates ranged from 10 to 91.7 percent (Fig. 3). A statistically significant difference was found between each study (p < 0.0001). We included amputations because of an infection and or recurrence of tumor in our calculation of the re-intervention rate for each study. Figure 3: Re-intervention rates per study: calculated means are represented by the blue squares; each square differs in size since the size of the square is representation of the numbers of patients included in the study. The blue error bares represent the 95% confidence interval.