Dolph Houben

79 Outcomes of vascularized bone allotransplantation 4 anastomoses were made (Fig. 1A). The AV-bundle was implanted in both groups but ligated in the control group (N=7). Rigid internal fixation was achieved with two orthogonal 2.7 mm 9-hole LCP plates (DePuy Synthes Vet, West Chester, PA) spanning the reconstruction (Fig.1B). A layered closure, use of Dermabond Prineo (Ethicon, LLC, San Lorenzo, Puerto Rico) and wrapping the hindlimb with Tegaderm and Ioban (3M Health Care, St Paul, MN) minimized the risk of deep wound infection. A central venous catheter (Hickman catheter, Bard Access Systems, Inc., Salt Lake City, UT) was placed in the internal jugular vein to enable intravenous drug administration and blood collection during the immunosuppressive period as described previously [18] . Figure 1: (A) schematic drawing of the orthotopic transplantation of a vascularized bone allograft model, (1) Allogenic pedicle with microanastomosis, (2) AV bundle entering the allotransplant into the intramedullary space, (3) Allogenic pedicle entering the nutrient foramen, (B) Post-operative radiographic image of the reconstruction.