Dolph Houben

Chapter 1 Introduction and Outline of the Thesis 11
Chapter 2 Vascularized bone grafts, a closer look at the free fibula flap for lower extremity reconstruction 31
Chapter 3 Combined massive allograft and intramedullary vascularized fibula as the primary reconstruction method for segmental bone loss in the lower extremity: a systematic review and meta-analysis 55
Chapter 4 Outcomes of vascularized bone allotransplantation with surgical induced autogenous angiogenesis in a large animal model: bone healing, remodeling and material properties 75
Chapter 5 Neo-angiogenesis, transplant viability and molecular analyses of vascularized bone allotransplantation surgery in a large animal model 95
Chapter 6 Transplant chimerism in porcine structural vascularized allotransplants 115
Chapter 7 Autogenous arteriovenous bundle implantation maintains viability without increased immune response in large porcine bone allotransplants 132
Chapter 8 A new porcine vascularized whole knee allotransplantation model: anatomy, surgical technique and improvements 155
Chapter 9 Summary and general discussion 173
Chapter 10 Summary in Dutch (Nederlandse samenvatting) 185
List of abbreviations 192
Curriculum Vitae 194
PhD Portfolio 196
Dankwoord / Credits 200

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