Josephine van Dongen

Chapter 4 100 Intention to treat (ITT) According to protocol (ATP) Pre-imple- mentation period: all infants N=631 $ Post-imple- mentation period: all infants N=851 $ p-value Pre-imple- mentation: willing to vaccinate N=496 Post-imple- mentation: vaccinated N=719 p-value Small for gestational age £ 176 (27.9%) 271 (31.8%) 0.10 135 (27.2%) 238 (33.1%) 0.03 Presence of severe congenital disorder * 126 (20.0%) 125 (14.7%) 0.01 95 (19.2%) 106 (14.7%) 0.04 Length of postnatal hospital stay (IQR) 29 days (44) 27 days (38) 0.53 31 days (43) 27 days (35) 0.17 Total hos- pitalization days during follow-up (IQR) 35 days (48) 33 days (42) 0.35 37 days (48) 31 days (41) 0.13 Vaccinat- ed within national im- munization program 539 (85.4%) 753 (88.5%) 0.08 484 (97.6%) 652 (90.7%) <0.001 Daycare ever 319 (56.5%) 464 (59.4%) 0.28 289 (58.6%) 398 (59.6%) 0.74 Average age at start in months (IQR) 6 (1-11) 5 (1-9) 0.06 6 (1-12) 5 (1-9) 0.01 Breastfed ever 355 (62.7%) 481 (61.4%) 0.61 312 (63.3%) 403 (602%) 0.29 Average duration of exclusive breastfeed- ing in weeks (SD) 16.8 (7.0) 16.3 (7.3) 0.40 16.6 (6.9) 16.4 (7.4) 0.69 Socieco- nomic status ^ Higher Moderate Lower 398 (71.3%) 134 (24.0%) 26 (4.7%) 568 (72.9%) 183 (23.5%) 28 (3.6%) 0.59 352 (71.5%) 119 (24.2%) 21 (4.3%) 492 (74.1%) 153 (23.0%) 19 (2.9%) 0.36