Josephine van Dongen

Chapter 6 148 Non-specific effect outcomes by vaccination status are described in table 2 . Twenty-one hospitalizations for acute gastroenteritis were excluded from the acute hospitalizations (eleven among unvaccinated and ten among vaccinated infants, respectively). Thir ty-nine percent of infants were hospitalized at least once or repor ted one month with eczema. For 82% of infants at least one ARI episode was repor ted. Incidence of any of the non-specific effect outcomes or the mean cumulative number of days hospitalized or with ARI symptoms show no significant differences ( table 2 ). Table 2 Non-specific effect outcomes for vaccinated and unvaccinated infants Pre-implementation: willing to vaccinate N=496 Post-implementation: vaccinated N=719 At least one acute hospitalization 212 (43.0%) 262 (39.2%) Cumulative number of hospitalizations 367 433 Incidence of hospitalization * (95%CI) 0.54 (0.48;0.59) 0.48 (0.43;0.52) Mean cumulative number of hospitalization days 8.3 8.2 At least one ARI 411 (83.4%) 584 (87.3%) Cumulative number of months with ARI 1888 2660 Incidence of months with ARI (95%CI) 2.77 (2.64;2.89) 2.92 (2.81;3.04) Mean cumulative number of days with ARI 23.2 24.5 At least one month with eczema 204 (41.4%) 270 (40.4%) Cumulative number of repor ted eczema 995 1215 Incidence of months with eczema (95%CI) 1.46 (1.37;1.55) 1.33 (1.26;1.41) Percentages are derived excluding cases with missing information (n=53). * Incidence per person year of observation. Abbreviations: N=number in group, CI = confidence interval and, ARI = acute respiratory illness.