151751-Najiba-Chargi

115 Surgery: skeletal muscle mass, systemic inflammation and flap reconstruction Supplemental figure 1. This figure displays two identical axial CT-slides at the level of C3; in the left axial slidemuscle tissue is unsegmented. The right CT slide shows both sternocleidomastoid and paravertebral muscles segmented in red Formula 1: CSA at L3 (cm 2 ) = 27.304 + 1.363 * CSA at C3 (cm 2 ) – 0.671*Age (years) + 0.640 * Weight (kg) + 26.442*Sex (Sex=1 for female and 2 for male) Formula 2: Lumbar SMI (cm 2 /m 2 ) = CSA at L3/length (m 2 ) SYSTEMIC INFLAMMATION NLR was used to evaluate systemic inflammation. According to literature, an NLR >3 indicates high grade of systemic inflammation. 32 OUTCOME VARIABLES Postoperative complications were defined as any adverse development after surgery. Se - verity of all complications were scored by use of the Clavien-Dindo classification of surgical complications. 31 Complications were also scored by distinction of flap-related complications and non-flap-related complications. Flap-related complications were defined as all complica - tions concerning the flap. Patients withmultiple complications were scored according to their highest grade of complication. Length of hospital stay (LOS) was defined as the time between date of operation and date of hospital discharge. Disease-free survival (DFS) was defined as the time between diagnosis date and recurrence date or last follow-up, whichever occurred first. Overall survival (OS) was defined as the time between diagnosis date and date of death or last follow-up, whichever occurred first. 7