151751-Najiba-Chargi

120 CHAPTER 7 Figure 1. Choice of flaps for reconstruction Of the 616 patients, pre-treatment imaging could be retrospectively retrieved for 413 patients (67%). Of these patients, 224 had low SMM (54.2%). All patients had available NLR data, 311 patients (50.5%) were identified with elevated systemic inflammation (NLR >3). SMM and NLR had a low significant correlation (r 2 =-0.13, p=0.01). Of the patients with available SMM status (n=413), 101 (24.5%) had no low SMM or elevated NLR, 101 (24.5%) had low SMMwithout elevat - ed NLR, 88 (21.3%) had no low SMM but had elevated NLR and 123 (29.8%) patients had both low SMM and elevated NLR. Table 1. provides information about the differences in variables between patients with low SMM and without low SMM and between patients with low NLR and elevated NLR. Patients with low SMMwere significantly more likely to be female, older of age, to have a BMI ≤18.5 kg/m 2 and to have lower hemoglobin levels, all p<0.01. Patients with elevated NLR were significantly more likely to be older of age, to have a BMI ≤18.5 kg/m 2 , more comorbidities, ECOG performance status ≥1, lower hemoglobin levels, lower eosinophil levels, lower monocytes level, lower albumin levels, higher levels of white blood cells, higher levels of c-reactive protein and a lower SMM index (all p<0.01). POST-OPERATIVE COMPLICATIONS Table 2. shows the types of flap and non-flap-related complications. All complications were graded by the Clavien-Dindo grading system. Of the 616 patients, 76 (12.3%) experienced a flap-related complication. Flap failure rate was 4.7%. Non-flap-related complications occurred in 243 patients (39.4%). Median time between operation date and complication date was 2 weeks (IQR 0.48-4.8 weeks).