151751-Najiba-Chargi

123 Surgery: skeletal muscle mass, systemic inflammation and flap reconstruction Table 3. Univariate and multivariate analysis for any surgical complications Variable Univariate analysis OR 95% CI p-value Multivariate analysis OR 95% CI p-value All oncological patients with known SMM status (n=387) Gender Female Male Ref. 1.2 0.8-1.8 0.4 Age (years) 1.0 1.0-1.0 0.3 Flap used Radial forearm Fibula Others Ref. 0.9 0.7 0.5-1.5 0.5-1.2 0.7 0.2 ACE-27 None Mild Moderate Severe Ref. 1.1 1.4 2.2 0.7-1.7 0.8-2.4 0.6-8.0 0.8 0.3 0.2 Ref. 0.4 0.5 0.6 0.1-1.6 0.1-1.7 0.1-2.2 0.2 0.2 0.4 BMI (kg/m 2 ) Normal (18.5-24.9) Underweight (≤ 18.5) Overweight (25-29.9) Obese (≥ 30) Ref. 0.7 0.9 1.1 0.3-1.5 0.6-1.5 0.6-2.0 0.3 0.8 0.7 Ref. 0.6 0.9 1.1 0.2-1.3 0.6-1.5 0.6-2.0 0.2 0.7 0.8 Smoking status * Never Current/former Ref. 0.9 0.6-1.3 0.5 Alcohol use * Never Current/former Ref. 1.0 0.7-1.5 0.9 Low hemoglobin , ≤ 100 g/L No Yes Ref. 2.0 0.8-4.8 0.2 Elevated NLR , > 3 No Yes Ref. 1.6 1.1-2.3 0.045 Ref. 1.5 1.01-2.3 0.04 Low albumin , ≤ 40 g/L No Yes Ref. 1.1 0.6-2.0 0.7 Low SMM ** No Yes Ref. 0.9 0.6-1.3 0.5 SMM and NLR Normal SMM and NLR Normal NLR, low SMM Normal SMM, NLR > 3 Low SMM and NLR > 3 Ref. 1.0 1.8 1.3 0.6-1.8 1.0-3.2 0.8-2.3 1.0 0.05 0.3 7

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