151751-Najiba-Chargi

128 CHAPTER 7 Figure 2. Kaplan Meier Survival curves for OS for all patients undergoing head and neck reconstruction according to NLR status (Log rank χ 2= 6.0, p=0.02) and SMM status (Log rank χ 2= 4.2, p=0.04) and for DFS for all patients undergoing head and neck reconstruction according to NLR status (Log rank χ 2= 4.4, p=0.04) and SMM status (Log rank χ 2= 1.7, p=0.2) Table 4. Univariate and multivariate cox proportional hazards model for prognostic factors for OS and DFS in early and advanced stage HNSCC Variable Univariate analysis HR 95% CI p-value Multivariate analysis 1 HR 95% CI p-value Multivariate analysis 2 HR 95% CI p-value Oncological HNSCC patients: TNM stage I=II - OS Gender Female Male Ref. 0.5 0.3-0.9 0.01 Age (years) 1.1 1.04-1.1 0.0001 ACE-27 score None Mild Moderate Severe Ref. 1.6 1.8 1.9 0.8-2.9 0.8-4.2 0.4-8.2 0.2 0.2 0.4 Ref. 1.6 1.5 2.2 0.9-3.0 0.7-3.6 0.5-9.5 0.1 0.3 0.3 Ref. 1.5 1.7 2.6 0.8-2.9 0.7-4.0 0.6-11.5 0.2 0.2 0.2 BMI (kg/m 2 ) 0.95 0.9-1.0 0.1 Hemoglobin (g/L) 0.99 0.97-1.0 0.2 Hemoglobin ≤100 (g/L) No Yes Ref. 1.8 0.2-13.2 0.6