151751-Najiba-Chargi

129 Surgery: skeletal muscle mass, systemic inflammation and flap reconstruction Table 4. (Continued) Variable Univariate analysis HR 95% CI p-value Multivariate analysis 1 HR 95% CI p-value Multivariate analysis 2 HR 95% CI p-value NLR ≤3.0 >3.0 Ref. 1.3 0.7-2.2 0.4 Low SMM No Yes Ref. 2.3 1.2-4.4 0.01 Ref. 2.3 1.2-4.4 0.01 SMM and NLR Normal SMM and NLR Normal NLR, low SMM Normal SMM, NLR > 3 Low SMM and NLR > 3 Ref. 1.6 0.7 2.7 0.7-2.6 0.2-2.3 1.2-6.3 0.3 0.5 0.02 Ref. 1.5 0.6 2.6 0.7-3.5 0.2-2.1 1.1-6.0 0.3 0.4 0.03 Oncological HNSCC patients: TNM stage III-IV - OS Gender Female Male Ref. 1.3 0.9-1.9 0.2 Age (years ) 1.0 1.0-1.0 0.7 ACE-27 score None Mild Moderate Severe Ref. 1.6 1.8 1.9 0.8-2.9 0.8-4.2 0.4-8.2 0.2 0.2 0.4 BMI (kg/m 2 ) 0.94 0.90-0.98 0.004 0.96 0.93-0.99 0.01 0.94 0.9-0.98 0.008 Hemoglobin (g/L) 0.99 0.98-0.99 0.02 0.99 0.98-0.99 0.03 Hemoglobin ≤100 (g/L) No Yes Ref. 1.5 0.8-2.6 0.2 NLR ≤ 3.0 >3.0 Ref. 1.2 0.8-2.2 0.4 Ref. 1.3 0.9-1.7 0.1 Low SMM No Yes Ref. 1.3 0.9-1.8 0.2 SMM and NLR Normal SMM and NLR Normal NLR, low SMM Normal SMM, NLR > 3 Low SMM and NLR > 3 Ref. 1.4 1.3 1.5 0.8-2.4 0.8-2.2 0.9-2.5 0.2 0.3 0.09 7