151751-Najiba-Chargi

149 Surgery: skeletal muscle mass and oral cavity cancer Table 5. (Continued) Potential risk factors Length of hospital stay ratio (95%-CI) p value Overall p value Sarcopenia Yes 1.0 (0.93 - 1.08) 0.93 - No Ref. Variables with p <0.25 were used in the multivariate analysis (indicated in bold) a ACE-27 = Adult Comorbidity Evaluation-27, b ASA classification = American Society of Anesthesiologists physical status classification system, c Hb = hemoglobin, d BMI = Body Mass Index All tumor variables appeared collinear with the operating time ( p < 0.001 for all variables). Therefore, the tumor variables were not included in multivariate analysis to prevent biased estimation. In the multivariate analysis, the presence of perioperative complications was associated with sarcopenia (OR 2.5, p<0.05), longer operating time (OR 1.4, p<0.001), increased blood loss (OR 1.5, p<0.01) and comorbidity (OR 9.1, p<0.05). The number of perioperative complications was associatedwith sarcopenia (OR 2.4, p<0.05) , longer operating time (OR 1.2, p<0.001), increased blood loss (OR 1.6, p<0.001) and comorbidity (ACE-27 score 3) (OR 6.3, p<0.01). Longer hospital stay was associated with longer operating time, decrease in hemoglobin level, ACE-27 and ASA (score 3). The ratios and p values are shown in Table 6 and 7. Table 6. Multivariate analysis of presence, number and severity (Clavien-Dindo grade) of perioperative complications for patient variables Patient variables Presence of perioperative complications Number of perioperative complications OR (95% CI) p value Incidence rate (95% CI) p value ACE-27 b 0 Ref. 0.11 a Ref. 0.03 a 1 2.52 (0.71-8.94) 0.15 1.89 (0.70-5.08) 0.21 2 1.95 (0.56-6.82) 0.30 1.64 (0.62-4.36) 0.32 3 9.08 (1.51-54.54) 0.02 6.21 (1.75-22.0) 0.005 ASA c 1 Ref. 0.33 a Ref. 0.33 a 2 0.96 (0.23-4.05) 0.96 0.84 (0.28-2.51) 0.75 3+ 1.93 (0.36-10.28) 0.44 1.39 (0.39-4.93) 0.62 Operating time 1.37 (1.21-1.56) <0.001 1.21 (1.11-1.32) <0.001 Decrease in Hb d level 1.55 (1.14-2.10) 0.005 1.63 (1.31-2.04) <0.001 Sarcopenia Yes 2.61 (1.12-6.08) 0.03 2.43 (1.24-4.78) 0.01 No Ref. Ref. Variables with p < 0.05 were considered significant. a Overall p value of the variable for the outcome b ACE-27 = Adult Comorbidity Evaluation-27, c ASA classification = American Society of Anesthesiologists physical status classification system, d Hb = hemoglobin 8