151751-Najiba-Chargi

184 CHAPTER 10 RESULTS PATIENT CHARACTERISTICS In total, 343 patients were included between January 2007 and December 2018. Seventeen patients were excluded, six of them did not had evaluable pre-treatment imaging and eleven patients eventually did not receive cisplatin based chemoradiotherapy. Table 1 shows the characteristics of the included patients. Of the included patients, 235 patients (68.5%) were male and the median age at diagnosis was 59.07 years (IQR 53.41-63.70). Table 1. Demographic, clinical and biochemical characteristics of patients according to SMM status and DLT status Characteristic Total N=343 Without low SMM n=144 41.98% With Low SMM n=199 58.01% Without DLT n=189 55.1% With DLT n=154 44.90% N, % Mean, SD N, % Mean, SD N, % Mean, SD p N, % Mean, SD N, % Mean, SD p Gender Male Female 235 (68.5) 108 (31.5) 139 (59.1) 5 (4.6) 96 (40.9) 103 (95.4) <0.01 141 (60) 48 (44.4) 94 (40) 60 (55.6) <0.01 Age diagnosis 57.7 (8.4) 55.5 59.4 <0.01 57.26 (8.6) 58.35 (8.2) 0.23 Smoking No Yes 61 (17.8) 282 (82.2) 35 (57.4) 109 (38.7) 26 (42.6) 173 (61.3) 0.01 34 (55.7) 155 (55.0) 27 (44.3) 127 (45.0) 1.0 Alcohol use No Yes 60 (17.5) 283 (82.5) 26 (43.3) 118 (41.7) 34 (56.7) 165 (58.3) 0.89 35 (58.3) 154 (54.4) 25 (41.7) 129 (45.6) 0.70 ACE-27 None Mild Moderate Severe 85 (24.8) 131 (38.2) 93 (27.1) 34 (9.9) 37 (43.5) 56 (42.7) 37 (39.8) 14 (41.2) 48 (56.5) 75 (57.3) 56 (60.2) 20 (58.8) 0.96 48 (56.5) 69 (52.7) 49 (52.7) 23 (67.6) 37 (43.5) 62 (47.3) 44 (47.3) 11 (32.4) 0.43 Performance ECOG 0 ECOG 1 ECOG ≥2 Unknown 93 (27.1) 144 (42) 38 (11.1) 68 (19.8) 50 (53.8) 60 (41.7) 14 (36.8) 20 (29.4) 43 (46.2) 84 (58.3) 24 (63.2) 48 (70.6) 0.02 52 (55.9) 77 (53.5) 19 950.0) 41 (60.3) 41 (44.1) 67 (46.5) 10 (50) 27 (39.7) 0.73 Albumin (g/L) 40 (4.9) 39.85(4.5) 38.36 (5.2) 0.04 38.44 (4.5) 39.50 (5.3) 0.14 Total protein (g/L) 71.2 (7.9) 72.29 (6.04) 70.35 (9.13) 0.41 72.5 (5.90) 68.47 (10.7) 0.10 Hemoglobin (mmol/L) 8.5 (1.1) 8.91 (0.99) 8.23 (1.01) <0.01 8.58 (1.10) 8.44 (0.99) 0.21