151751-Najiba-Chargi

324 CHAPTER 17 Table 1. (Continued) t 0 n = 108 t 1 n = 99 t 2 n = 71 P value t 0, t 1, t 2 Only t 0 available n = 34 P value t 0, only t 0 Not included because no t0 available n = 84 P value t 0, no t 0 Unknown 5 4 2 4 12 Treatment modality RT 39 (36) 36 (36) 26 (37) .973 b 9 (27) .384 b 33 (39) .481 b RT unfit for chemo 3 (3) 3 (3) 2 (3) 2 (6) 6 (7) CRT (cetuximab) 17 (16) 17 (17) 11 (16) 7 (21) 12 (14) CRT (cisplatin) 49 (45) 43 (43) 32 (45) 16 (47) 33 (39) Modified diet at t 0 (FOIS < 7) No 89 (82) 81 (82) 66 (93) .090 b 23 (72) .212 d NA Yes 19 (18) 18 (18) 5 (7) 9 (28) Unknown 0 0 0 2 Trismus at t 0 No 98 (94) 91 (96) 64 (94) 1.000 b 21 (66) <.001 d NA Yes 6 (6) 4 (4) 4 (6) 11 (34) Unknown 4 4 3 2 NB: Not all percentages sum up exactly to 100% due to rounding. Abbreviations: BMI = body mass index, CRT = chemoradiotherapy (cisplatin or cetuximab based), HPV = human papilloma virus, FOIS = functional oral intake scale, other = soft palate, uvula, oropharyngeal wall, vallecula or pharyngeal arch, RT = radiotherapy, SMM = skeletal muscle mass, t0 = pretreatment, t1 = six months after treatment, t2 = twelve months after treatment, sarcopenia = SMM below 43.2 cm 2 /m 2 .

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