151751-Najiba-Chargi

334 CHAPTER 17 SPEECH AND VOICE OUTCOMES Speech and voice outcomes are presented in figure 3c and table 4. Vowel space area decreased significantly from t 0 to t 1, and not significantly from t 1 to t 2, indicating worsening articulation. Articulation rate and voice quality (AVQI) did not change significantly over time. Significantly more patients had speech related problems in daily life, as assessed with the SHI, at t 1 com- pared to t 0. Speech and voice outcomes stratified by treatment modality are presented in figure 4c and appendix 5. Patients treated with RT+ more often had a vowel space below 80%, indicating abnormal articulation, at t 0, t 1 and t 2. SHI scores were comparable for patients treated with RT and RT+. FACTORS ASSOCIATED WITH FUNCTIONAL LIMITATIONS Appendix 6 shows the baseline characteristics stratified by patients who did or did not have a modified diet (FOIS < 7) at t 2. A modified diet at t 2 was univariably associated with pre- treatment lower BMI, lower SMI, sarcopenia, and a T4 tumor. Appendix 7 shows the baseline characteristics stratified by patients who had trismus (mouth opening < 36 mm) at t 2. Trismus at t 2 was univariably associated with tumor site other than base of tongue and tonsil (i.e., soft palate, uvula, pharyngeal wall, vallecula, and pharyngeal arches). Appendix 8 shows the baseline characteristics stratified by patients who had a vowel space below 80%, indicating abnormal articulation, at t 2. A vowel space below 80% at t 2 was univariably associated with a pretreatment vowel space area below 80% only.