151751-Najiba-Chargi

36 CHAPTER 2 measures model with absolute agreement. The ICCs were rated as poor (0.00 – 0.49), fair to good (0.50 – 0.74), good (0.75-0.90) and excellent (>0.90). 18 For agreement in classification of patients with low SMM, Cohen’s κ was used. The agreement was rated as no agreement (<0), slight (0.01-0.20), fair (0.21 - 0.40), moderate (0.41 - 0.60), substantial (0.61 - 0.80) and almost perfect (0.81 - 1.00). 19 A two-tailed test of significance ( p = 0.05) was used. RESULTS PATIENT CHARACTERISTICS For this study, 200 patients were included for analyses. Baseline patient characteristics are shown in Table 1. Patients were predominantly male and often presented with advanced dis - ease (T3-4; N+). Weight and body mass index (BMI) at diagnosis were normally distributed. On average, patients had a normal BMI. Table 1. Patient characteristics Characteristic n (% or SD), total n = 200 Gender Male Female 147 (73.5) 53 (26.5) Age at diagnosis (years) Mean (SD) Range 63.5 (8.3) 44.9–85.6 Weight at diagnosis (kg) Mean (SD) Range 74.1 (16.4) 40.0–122.0 Body mass index (weight/height 2 ) Mean (SD) Range 24.2 (4.6) 14.0–40.0 Localization Oral cavity Nasopharynx Oropharynx Hypopharynx Larynx Unknown primary 12 (6.0) 5 (2.5) 83 (41.5) 57 (28.5) 40 (20.0) 3 (1.5) T-status T1-2 T3-4 92 (46.0) 108 (54.0) N-status N0 N1-2a N2b-3b 73 (36.5) 61 (30.5) 66 (33.0) M-status M0 M+ Mx 183 (91.5) 10 (5.0) 7 (3.5)

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