151751-Najiba-Chargi

367 The elderly head and neck cancer patient: sarcopenia and survival Table 1. (Continued) Characteristics Frequencies n, (%) or Mean (SD) MUST-score <2 ≥2 66 (77.6) 19 (22.4) TNM-stage I II III IV 11 (12.9) 19 (22.4) 16 (18.8) 39 (45.9) Tumor type Primary Second primary Recurrent 65 (76.5) 6 (7.1) 14 (16.5) Tumor site Oral cavity Nasopharynx Oropharynx* Hypopharynx Larynx Skin Salivary glands Paranasal sinuses 52 (61.2) 2 (2.4) 5 (5.9) 3 (3.5) 8 (9.4) 12 (14.1) 1 (1.2) 2 (2.4) Treatment intention Curative Palliative 71 (83.5) 14 (16.5) Legend: *. Four patients had HPV-negative oropharyngeal cancer; one patient had missing data on HPV- status. Of the 85 included patients; 69 patients (81.2%) had low SMI, 50 patients (58.8%) had lowHGS, and 58 patients (68.2%) had low gait speed. Forty-one patients (48.2%) were classified as sar - copenic; of these patients 31 patients (75.6%) had low SMI in combination with low HGS and low gait speed, 6 patients (14.6%) had low SMI in combination with low gait speed and normal HGS, and 4 patients (9.8%) had low SMI in combination with low HGS and normal gait speed. Table 2 and table 3 show the general characteristics and the hematological and biochemical markers of the included patients according to the presence or absence of sarcopenia. Patients with sarcopenia weremost likely to smoke (77.8% versus 22.2%; LR 8.37, p=0.02), to have lower mean hemoglobin levels at diagnosis (8.09 mmol/L (SD 1.06) versus 8.67 mmol/L (SD 1.12); p=0.03) and to die (63.6% versus 36.4%; LR 5.17, p<0.01). 18

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