151751-Najiba-Chargi

373 The elderly head and neck cancer patient: sarcopenia and survival Table 5. Univariate and multivariate analysis of the hazard ratios for sarcopenia, age, Hb level, BMI, MUST-score, CCI and TNM-stage as independent prognostic factors for overall survival. Variable Overall survival Univariate analysis Multivariate analysis (*) Model 1 Model 2 HR 95% CI P-value HR 95% CI P-value HR 95% CI P-value Sarcopenia 2.80 1.14-6.88 0.03* 2.66 1.07-6.58 0.04* 1.36 0.48-3.83 0.56 Age (years) 1.03 0.95-1.11 0.48 1.02 0.94-1.11 0.59 1.05 0.97-1.13 0.26 Hb (mmol/L) 0.82 0.58-1.16 0.26 0.90 0.61-1.32 0.58 BMI (kg/m 2 ) <18.5 18.5-25 25-30 ≥30 - Ref. 0.54 0.34 - 0.21-1.38 0.10-1.20 - 0.20 0.10 - Ref. 0.54 0.45 - 0.21-1.39 0.12-1.64 - 0.20 0.23 - Ref. 0.50 0.70 - 0.19-1.31 0.18-2.72 - 0.16 0.61 MUST-score <2 ≥2 Ref. 1.75 0.68-4.53 0.25 Ref. 1.36 0.47-3.95 0.57 CCI <6 ≥6 Ref. 1.22 0.52-2.86 0.65 Ref. 0.92 0.35-2.40 0.86 Ref. 1.47 0.58-3.74 0.42 TNM-stage I II III IV Ref. 0.96 5.24 15.64 0.06-15.40 0.57-48.46 1.99-122.88 0.98 0.14 0 .01* - - - Ref. 0.96 5.24 15.64 0.06-15.40 0.57-48.46 1.99-122.88 0.98 0.14 0.01* Legend: *. Correlation is significant at the 0.05 level (2-tailed) (*) Model 1 includes the variables; sarcopenia, age, hb value, BMI, MUST-score and CCI. Model 2 includes the variables; sarcopenia, age, BMI, CCI and TNM-stage. 18