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377 The elderly head and neck cancer patient: sarcopenia and survival REFERENCES 1. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on defini- tion and diagnosis: Report of the Europe- an Working Group on Sarcopenia in Older People. Age Ageing . 2010;39(4):412-423. doi:10.1093/ageing/afq034 2. von Haehling S, Morley JE, Anker SD. An overview of sarcopenia: facts and num- bers on prevalence and clinical impact. J Cachexia Sarcopenia Muscle . 2010;1(2):129- 133. doi:10.1007/s13539-010-0014-2 3. Rolland Y, Van Kan GA, Gillette-Guyonnet S, Vellas B. Cachexia versus sarcopenia. Curr Opin Clin Nutr Metab Care . 2011;14(1):15-21. doi:10.1097/MCO.0b013e328340c2c2 4. Goodpaster BH, Park SW, Harris TB, et al. The loss of skeletal muscle strength, mass, and quality in older adults: The Health, Aging and Body Composition Study. Journals Gerontol - Ser A Biol Sci Med Sci . 2006;61(10):1059-1064. doi:10.1093/ gerona/61.10.1059 5. Janssen I, Baumgartner RN, Ross R, Rosen - berg IH, Roubenoff R. Skeletal Muscle Cut - points Associated with Elevated Physical Disability Risk in Older Men and Women. Am J Epidemiol . 2004;159(4):413-421. doi:10.1093/aje/kwh058 6. Shachar SS, Williams GR, Muss HB, Nishijima TF. Prognostic value of sarcopenia in adults with solid tumours: A meta-analysis and systematic review. Eur J Cancer . 2016;57:58- 67. doi:10.1016/j.ejca.2015.12.030 7. Wendrich AW, Swartz JE, Bril SI, et al. Low skeletal muscle mass is a predictive factor for chemotherapy dose-limiting toxicity in patients with locally advanced head and neck cancer. Oral Oncol . 2017;71:26-33. doi:10.1016/j.oraloncology.2017.05.012 8. Prado CMM, Baracos VE, McCargar LJ, et al. Sarcopenia as a determinant of chemother- apy toxicity and time to tumor progression inmetastatic breast cancer patients receiv- ing capecitabine treatment. Clin Cancer Res . 2009;15(8):2920-2926. doi:10.1158/1078- 0432.CCR-08-2242 9. Antoun S, Baracos VE, Birdsell L, Escudier B, Sawyer MB. Low body mass index and sarcopenia associated with dose-limiting toxicity of sorafenib in patients with renal cell carcinoma. Ann Oncol . 2010;21(8):1594- 1598. doi:10.1093/annonc/mdp605 10. AchimV, Bash J, Mowery A, et al. Prognostic Indication of Sarcopenia for Wound Com - plication After Total Laryngectomy. JAMA Otolaryngol Neck Surg . 2017;143(12):1159. doi:10.1001/jamaoto.2017.0547 11. Bril SI, Pezier TF, Tijink BM, Janssen LM, Braunius WW, Bree R. Preoperative low skeletal muscle mass as a risk factor for pharyngocutaneous fistula and decreased overall survival in patients undergoing total laryngectomy. Head Neck . 2019;41(6):1745- 1755. doi:10.1002/hed.25638 12. Ida S, Watanabe M, Yoshida N, et al. Sar - copenia is a Predictor of Postoperative Respiratory Complications in Patients with Esophageal Cancer. Ann Surg Oncol . 2015;22(13):4432-4437. doi:10.1245/s10434- 015-4559-3 13. van Vugt JLA, Braam HJ, van Oudheusden TR, et al. Skeletal Muscle Depletion is Asso - ciatedwith Severe Postoperative Complica- tions in Patients Undergoing Cytoreductive Surgery with Hyperthermic Intraperitone - al Chemotherapy for Peritoneal Carcino- matosis of Colorectal Cancer. Ann Surg Oncol . 2015;22(11):3625-3631. doi:10.1245/ s10434-015-4429-z 18