151751-Najiba-Chargi

387 The elderly head and neck cancer patient: sarcopenia and frailty Table 1. Characteristics of HNC patients with and without frailty [1] Total N=150 Frail N=60 Non-Frail N=90 χ 2 p-value Age (years) (M, SD) 70.3 7.26 71.5 8.7 69.5 6.0 NA 0.14 Sex (n, %) Male 101 67 36 60 65 72 2.45 0.1 Female 49 33 24 40 25 28 Weight loss 6 months prior to diagnosis (n, %) Non 117 78 40 66 77 86 13.23 0.001* <10% 26 17 13 22 13 14 ≥ 10% 7 5 7 12 0 0 BMI (kg/m 2 ) (n, %) <20 53 35 26 43 27 30 21.03 0.000* 20-24.9 9 6 9 15 0 0 25-29.9 64 43 20 33 44 49 ≥ 30 24 16 5 9 19 21 Smoker (n, %) No 26 17 10 17 16 18 1.67 0.434 Former 73 49 26 43 47 52 Current 51 34 24 40 27 30 Alcohol use (n, %) No 29 18 11 18 18 20 0.27 0.88 Yes 101 62 40 67 61 68 Former 20 12 9 15 11 12 ACE-27 score (n, %) Non 49 33 12 20 37 41 11.93 0.008* Mild 54 36 21 35 33 37 Moderate 29 19 15 25 14 15 Severe 18 12 12 20 6 7 Localization (n, %) Oral cavity 32 21 13 22 19 21 5.40 0.71 Nasal cavity 6 4 3 5 3 3 Nasopharynx 6 4 2 3 4 5 Oropharynx 37 25 19 31 18 20 Hypopharynx 11 7 5 8 6 7 Larynx 29 19 10 17 19 21 Salivary glands 17 11 5 9 12 13 Skin 2 1 0 0 2 2 19