151751-Najiba-Chargi

392 CHAPTER 19 Table 3. Univariate and multivariate logistic regression analysis for analyzing variables associated with frailty in patients with HNC[3] Frailty Univariate analysis Multivariate analysis OR 95% CI P-value OR 95% CI P-value OR 95% CI P-value Age (years) <70 Ref. ≥ 70 1.20 0.62-2.29 0.59 Gender Male Ref. Female 1.73 0.87-3.46 0.12 ACE-27 score Non Ref. Ref. Ref. Mild 1.96 0.84-4.59 0.12 1.62 0.67-3.94 0.29 1.90 0.75-4.81 0.17 Moderate 3.30 1.24-8.78 0.02** 2.80 1.03-7.63 0.04** 3.59 1.21-10.60 0.002* Severe 6.17 1.90-20.00 0.002* 5.47 1.67-18.0 0.01* 8.08 2.21-29.60 0.003* TNM Stage I Ref. II 0.47 0.14-1.62 0.23 III 1.38 0.46-4.16 0.57 IV 1.88 0.70-5.04 0.21 Handgrip strength 0.94 0.90-0.97 0.000* 0.97 0.93-1.02 0.21 SMI 0.92 0.87-0.96 0.000* 0.92 0.86-0.98 0.01* Sarcopenia No Ref. Ref. Yes 2.84 1.10-7.34 0.03** 2.29 0.83-6.28 0.11 Table 4. Univariate and multivariate logistic regression analysis for analyzing variables associated with sarcopenia in patients with HNC[4] Sarcopenia Univariate analysis Multivariate analysis OR 95% CI P-value OR 95% CI P-value Age (years) <70 Ref. Ref. ≥ 70 3.68 1.27-10.64 0.02** 3.65 1.25-10.71 0.02** Gender Male Ref. Female 0.59 0.23-1.54 0.29 Weight loss 6 months prior to diagnosis Non Ref.