151751-Najiba-Chargi

60 CHAPTER 4 RESULTS SEARCH AND INCLUSION In total 139 patients who had undergone a CT-scan were screened for study viability. Of these patients 15.2% (n=21) had (partially) missing imaging and were subsequently excluded. Fur - thermore, in 3.6% (n=5) of included patients the available imaging was of insufficient quality for analysis either due to low resolution or poor image quality. In total, 113 whole body FDG- PET/CT-scans were included for further image analysis. PATIENT CHARACTERISTICS In total 113 patients were included, with a median age of 61.9 (IQR 56.0 – 68.40) years. Of the included patients, 81 (71.3%) were male. A minority of patients had no history of alcohol con - sumption (n=32, 28.3%) or smoking (n=6, 14.2%). Forty-six patients (40.7%) were categorized as having normal weight based on body mass index score (BMI). Most patients presented with a primary tumor (n= 99, 87.6%), commonly localized in the oropharynx (n= 73, 64.6%) of which 16 (14.2%) were HPV-positive. Most patients presented with a clinical TNM stage IV tumor (n= 71, 62.8%) and patients were most commonly treated with a combination of radiother - apy and systemic therapy (n= 53, 46.9%, Table 1). Twenty-nine patients were designated as “LowMSMI” and eighty-four as “Normal MSMI”. There was a statistically significant difference between these groups for L3 SMI, C3 CSA and BMI (p = 0.001, 0.007 and, 0.003, respectively). Table 1. Baseline characteristics of included patients and differences between normal and lowmasseter muscle index Characteristics All patients (n = 113) N (%) or Mean (±SD) Normal MSMI (n = 84) N (%) or Mean (±SD) Low MSMI (n = 29) N (%) or Mean (±SD) p-value Median age (years) (IQR) 61.7 (56.0 – 68.4) 63.0 (55.9 – 69.2) 61.4 (56.6 – 64.6) 0.3 Male 81 (71.7) 61 (72.6) 20 (69.0) 0.8 Deceased 43 (53.1) 41 (48.2) 19 (67.9) 0.08 Alcohol intake 0.5 Never 32 (28.3) 23 (27.4) 9 (31.0) Light (≤1 units/day) 26 (23.0) 17 (20.2) 9 (31.0) Moderate (>1-<4 units/day) 32 (28.3) 26 (31.0) 6 (20.7) Heavy (>4 units/day) 23 (20.4) 18 (21.4) 5 (17.2) Smoking status Never 16 (14.2) 15 (17.9) 1 (3.4) Current 57 (50.4) 36 (42.9) 21 (72.4)