151751-Najiba-Chargi

63 Diagnostics: measuring skeletal muscle mass of the musculus masseter Table 2. Body composition measurements Characteristic Total (n=113) Male (n=81) Female (n=32) p BMI at diagnosis Median (IQR) [Range] 24.2 (20.8–26.6) [14.9-40.0] 24.6 (21.8– 26.8) [14.9–38.4] 21.8(18.7 – 25.9) [15.8- 40.1] 0.02 BSA at diagnosis Mean (SD) [Range] 3.6 (0.9) [1.7–6.5] 3.9(0.9) [1.7–6.5] 3.0 (0.8) [2.0– 5.8] <0.001 Muscle CSA L3 (cm 2 ) Mean (SD) [Range] 139.6 (30.4) [65.3–235.0] 148.9 (28.5) [85.4–235] 116.2 (21.0) [65.3–158.5] <0.001 Muscle CSA C3 (cm 2 ) Mean (SD) [Range] 38.0 (8.5) [19.0– 58.8] 40.8 (7.7) [25.9–58.8] 30.8 (5.9) [19.0–44.7] <0.001 Muscle CSA masseter (mm 2 ) Mean (SD) [Range] 395.3 (84.3) [234.1–624.4] 415.7 (85.5) [243.0–624.4] 343.8 (54.7) [234.1–509.1] <0.001 Masseter volume (cm 3 ) Mean (SD) [Range] 18.2 (5.5) [8.3– 36.1] 19.4 (5.3) [8.4–36.1] 15.2 (4.9) [9.0–30.2] <0.001 Masseter maximum thickness (mm) Median (IQR) [Range] 12.8 (10.8 – 15.0) [8.5–21.1] 13.9 (11.1-15.4) [8.5–21.1] 11.4 (10.3 – 12.8) [8.9–18.0] 0.001 HU tot Median (IQR) [Range] 110.2 (95.0 – 128.4) [59.5-474.0] 111.8 (95.7– 129.3) [61.7–192.3] 104.9 (89.6–127.0) [59.5–474.0] 0.3 HU ROI (HU) Median (IQR) [Range] 56.2 (48.2– 65.6) [22.0-310.6] 56.9 (49.4 – 65.5) [28.8–310.6] 52.3 (46.6– 60.9) [22.0–83.2] 0.07 L3 SMI (cm 2 /m 2 ) Mean (SD) [Range] 45.4 (8.1) [39.8-50.8] 47.2 (7.9) [27.4–65.1] 41.0 (6.9) [23.7–52.8] <0.001 MSMI (mm 2 /m 2 ) Mean (SD) [Range] 129.0 (24.1) [75.4-189.3] 132.1 (26.0) [75.4–189.3] 121.2 (16.3) [80.1– 148.1] <0.001 Comparison of body composition measurements between sexes. Statistically significant differences are shown in bold. 4