151751-Najiba-Chargi

98 CHAPTER 6 STATISTICAL ANALYSIS Data analyses was performed using IBMSPSS statistics 25. Descriptive statistics for continuous variables with a normal distribution were presented as mean with standard deviation (SD). Variables with a skewed distribution were presented as median with interquartile range (IQR). Categorical variables were presented as frequencies and percentages. Survival was visual - ized using Kaplan Meier survival curves and number at risk tables. Cox proportional hazard regression model was used for univariate and multivariate analysis of survival and surgical complications. Covariates used in the multivariate analysis were selected based on clinical significance or selected based on statistical significance (p < 0.05) in univariate cox regression analysis. Statistical significance was evaluated at the 0.05 level using two-sided tests. RESULTS PATIENT CHARACTERISTICS Descriptive data are presented in table 1. In total, 78 patients were included. Of these patients, 75 (96.1%) patients had squamous cell carcinoma, 2 (2.6%) patients had sarcoma and 1 (1.3%) patient had adenoid cystic carcinoma. Low SMMwas identified in 48 (61.5%) patients. Patients with low SMM were more likely to be female and to have a normal BMI. Table 1. General characteristics of patients with and without low SMM Variables All patients N=78 Low SMM N=48 Without low SMM N=30 p-value Gender (n, %) Female Male 24 (30.8) 54 (69.2) 24 (50.0) 24 (50.0) - 30 (100) 0.0001** Age (years) (M, SD) 62.4 (10.2) 63.3 (10.9) 60.9 (8.8) 0.31 Body mass index (kg/m 2 )(n, %) <18.5 kg/m 2 18.5-24.9 kg/m 2 25-29.9 kg/m 2 ≥ 30 kg/m 2 20 (25.6) 27 (34.6) 26 (33.3) 5 (6.4) 8 (17.6) 27 (56.3) 12 (25.0) 1 (2.1) 12 (40.0) - 14 (64.7) 4 (13.3) 0.004** Smoker (n, %) No Yes 32 (41.0) 46 (59.0) 19 (39.6) 29 (60.4) 13(43.3) 17 (56.7) 0.82 ACE-27 score (n, %) None Mild Moderate Severe 28 (35.9) 19 (24.4) 27 (34.6) 4 (5.1) 18 (37.5) 12 (25.0) 15 (31.3) 3 (6.3) 10 (33.3) 7 (23.3) 12 (40.0) 1 (3.3) 0.86 Diagnosis Squamous cell carcinoma Osteosarcoma Adenoid cystic carcinoma 75 (96.1) 2 (2.6) 1 (1.3) 46 (95.8) 2 (4.2) - 29 (96.7) - 1 (3.3) 0.29