Yoeri Bemelmans

Safety and efficacy of outpatient hip and knee arthroplasty 101 7 Figure 3. Risk-of-bias assessment for randomized studies, with use of the Cochrane risk-of-bias tool. Randomization process Deviations from intended interventions Missing outcome data Measurement of the outcome Selection of the reported result Overall Goyal et al. 2016 Low risk Some concerns High risk + + + ? + + + ? — Heterogeneity Themethodological structure, measured outcomes, and description of data types varied between studies. Only studies that used comparable outcomes with a similar description of data were included in a meta-analysis. Data were pooled for total complication rates, SAEs, AEs, and readmissions. In OS studies, demographics on the distribution of gender, BMI, and type of anesthesia were homogeneous, whereas data on age and ASA class were highly heterogeneous. All data on primary outcomes (e.g. total complication rate, (S)AEs and readmission rates) were homogeneous. In SOS studies, all data on total complication rate, SAEs, readmission rates and demographics (age, gender, BMI, ASA, and type of anesthesia) showed heterogeneity. Subanalysis on AEs for THA, showed homogeneity. Data on PROMs and costs were analysed in a qualitative method. Demographic data Demographics were pooled and presented in the supplementary data. Within the OS studies, patients were significantly younger (P=0.009), had a lower BMI (P<0.001), and had a lower ASA class (P=0.002) compared to patients in the inpatient pathways. Patients in the SOS studies were significantly younger (P=0.002) andwere significantly more likely to be female (P=0.03) compared to patients in the inpatient pathways. The amount of ASA score> II patients, between the SOS pathways and inpatient pathways was not statistically significant different (P=0.13).