Yoeri Bemelmans

Local infiltration analgesia in knee arthroplasty 51 4 (80 %) in the Ropi+ group compared to 15 patients (60 %) in the Ropi− group were discharged before postoperative day 3 (n.s.). AE’s are summarized in Table 3. There were no thromboembolic or prosthesis related AE’s although one patient in the Ropi+ group underwent electric cardioversion due to atrial fibrillation and was discharged on postoperative day 3. At 3-month follow-up, the mean WOMAC and OKS significantly (P < 0.00) improved within each group with a mean of 30.7 (22.6) and 15.5 (10.9) in the Ropi+ group and 23.5 (25.3) and 12.5 (10.8) in the Ropi− group. There were no significant differences between both groups for both PROMS. Table 2. Baseline demographics and OR data presented as mean (SD) or absolute number between the groups. Variables Ropi + Ropi- Age (years) at index surgery 62.8 (6.1) 66.3 (9.8) Gender M/F 14/11 10/15 BMI kg/m 2 27.6 (5.7) 29.6 (3.8) ASA classification I/II/III 7/17/1 6/19/0 Operative data General/ Spinal 2/23 6/19 Blood loss ml 251.1 (97.7) 235.4 (96.1) OR time min 62.4 (12.1) 63.0 (15.1) VAS pain scores were not significantly different (Fig. 1). Thirteen patients (52 %) in the Ropi− group used rescue medication on postoperative day one compared to 7 patients (28 %) in the Ropi+ group (n.s.). Table 3. The amount of AE’s between both groups were not significant different. All adverse events occurred during initial admission except for the readmissions (*) AE’s Ropi + Ropi- Remarks Patient related 10 6 PONV, vasovagal syncope, electric cardioversion, delirium Wound disorders 3 0 Major wound leakage Surgical related 3 1 Loss of sensibility due to delayed recovery from anesthesia, limited knee flexion*, superficial wound infection*